GIURISATO EMANUELE

Emanuele
Giurisato
Dipartimento di Biotecnologie, Chimica e Farmacia
Professore Associato

Contatti

giurisato2@unisi.it
0577232125 [int.2125]
Lezioni a distanza

Curriculum Vitae

cv

Attività didattica

ANNO ACCADEMICO DI ESPLETAMENTO: 2025/2026

ANNO ACCADEMICO DI ESPLETAMENTO: 2024/2025

ANNO ACCADEMICO DI ESPLETAMENTO: 2023/2024

PATOLOGIA GENERALE E TERMINOLOGIA MEDICA
Anno di corso: 2 Laurea Magistrale Ciclo Unico 5 anni CHIMICA E TECNOLOGIA FARMACEUTICHE A.A. 2022/2023
TERAPIA DEL DOLORE: ASPETTI PATOLOGICI
Anno di corso: 3 FARMACIA OSPEDALIERA A.A. 2021/2022

ANNO ACCADEMICO DI ESPLETAMENTO: 2022/2023

PATOLOGIA GENERALE E TERMINOLOGIA MEDICA
Anno di corso: 2 Laurea Magistrale Ciclo Unico 5 anni CHIMICA E TECNOLOGIA FARMACEUTICHE A.A. 2021/2022

Iscrizione agli esami

Attività di ricerca

  • Filiberti S, Russo M, Lonardi S, Bugatti M, Vermi W, Tournier C, and Giurisato E . (2022) Self-Renewal of Macrophages: Tumor-Released Factors and Signaling Pathways. Biomedicines. Oct 26;10(11):2709. doi: 10.3390/biomedicines10112709.PMID:36359228
  • Zhang J, Pearson A, Sabherwal N, Telfer B, Ali N, Kan K, Xu Q, Zhang W, Chen F, Li S, Wang J, Gray N, Risa-Ebrí B, Finegan KG, Cross M, Giurisato E, Whitmarsh A, and Tournier C. (2022). Inhibiting ERK5 overcomes breast cancer resistance to anti-HER2 therapy by targeting the G1/S cell cycle transition. Cancer Research Communications 2(3): 131-145; doi.org/10.1158/2767-9764.CRC-21-0089.
  • Monti M, Celli J, Missale F, Cersosimo F, Russo M, Belloni E, Di Matteo A, Lonardi S, Vermi W, Ghigna C, and Giurisato E. (2022) Clinical Significance and regulation of ERK5 expression and function in Cancer. Cancers, 14(2), 348; https://doi.org/10.3390/cancers14020348
  • Cersosimo F, Barbarino M, Lonardi S, Vermi W, Giordano A, Bellan C and Giurisato E (2021).Mesothelioma malignancy and the microenvironment: molecular mechanisms. Cancers Nov 12;13(22):5664. doi: 10.3390/cancers13225664.
  • Xu Q, Zhang J, Telfer B, Zhang H, Ali N, Chen F, Risa B, Pearson AJ, Zhang W, Finegan KG, Ucar A, Giurisato E, and Tournier C (2021). The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion. Oncogene, 40(23):3929-3941. doi: 10.1038/s41388-021-01798-2.
  • Cersosimo F, Lonardi S, Bernardini G, Telfer B, Mandelli GE, Santucci A, Vermi W, and Giurisato E (2020). Tumor-Associated Macrophages in Osteosarcoma: from mechanisms to therapy. Int. J. Mol. Sci. 21(15), 5207; doi.org/10.3390/ijms21155207.
  • Giurisato E, Lonardi S, Telfer B, Lussoso S, Risa-Ebrí B, Zhang J, Russo I, Wang J, Santucci A, Finegan KG, Gray NS, Vermi W, and Tournier C. (2020). Extracellular-regulated protein kinase 5-mediated control of p21 expression promotes macrophage proliferation associated with tumor growth and metastasis. Can Research Jun 19:canres.2416.2019. doi: 10.1158/0008-5472.CAN-19-2416.
  • Luiz JP, Toller-Kawahisa J, Viacava P, Nascimento D, Pereira P, Saraiva AL, Prado D, Le Bert M, Giurisato E, Tournier C, Cunha TM, Cunha FQ, Quesniaux V, Ryffel B, Alves-Filho JC. (2020). MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. J Leukoc Biol July 22. doi:10.1002/JLB.1MA0520-016R.
  • Consoli F, Barbieri G, Picciolini M, Medicina D, Bugatti M, Tovazzi V, Liserre B, Zambelli C, Zorzi F, Berruti A, Giurisato E and Vermi W (2020). Clinical and molecular characterization of a rare complex BRAF mutation involving codon V600 and K601 in primary cutaneous melanoma. Frontiers of Oncology, doi.org/10.3389/fonc.2020.01056.
Ricerca

Pubblicazioni in evidenza:

  • J Pearson, A., Fullwood, P., Toro Tapia, G., Prise, I., Smith, M., Xu, Q., et al. (2020). Discovery of a gatekeeper residue in the C terminal tail of the extracellular signal-regulated protein kinase 5 (ERK5). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(3) [10.3390/ijms21030929]. - dettaglio
  • Moretti, E., Collodel, G., Belmonte, G., Noto, D., Giurisato, E. (2019). Defective spermatogenesis and testosterone levels in kinase suppressor of Ras1 (KSR1)-deficient mice. REPRODUCTION FERTILITY AND DEVELOPMENT, 31(8), 1369-1377 [10.1071/RD18386]. - dettaglio
  • Benerini Gatta, L., Melocchi, L., Bugatti, M., Missale, F., Lonardi, S., Zanetti, B., et al. (2019). Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome. CANCERS, 11(9) [10.3390/cancers11091219]. - dettaglio
  • Giurisato, E., Xu, Q., Lonardi, S., Telfer, B., Russo, I., Pearson, A., et al. (2018). Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(12), E2801-E2810 [10.1073/pnas.1707929115]. - dettaglio
  • Andrew S., G., Paula I., S., Poppy Sephton, C., Aleksandra, B., Richard, H., Giurisato, E., et al. (2017). Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5. SCIENCE ADVANCES, 3(8), Article number e1700898 [10.1126/sciadv.1700898]. - dettaglio
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