My work mostly focuses on two main ongoing projects:
1) Study of the reciprocal interactions among calcium signaling proteins in the plasma membrane-endoplasmic reticulum junctions (ER-PM junctions) microdomain in muscle and neurons, with particular emphasis on junctophilin and voltage-dependent calcium channels (CaVs) and calcium release channels (RyRs).
2) Strategies for the in-vivo administration of muscle-specific mirco-RNAs and their protective effects on the structure, function, and metabolism of muscle from mice affected by congenital myopathies.