Professore Ordinario

Office hours

  • Friday from 11:30 to 12:30
    Place: Stanza 10167, Polo Scientifico S. Miniato, si prega di inviare e-mail per verificare la disponibilità. Per motivi di sicurzza il docente riceve presso l'aula virtuale del sito docente (https://docenti.unisi.it/it/butini) secondo le stesse modalità
  •  If didactic activities are scheduled on Friday at the indicated time (please check the lessons' timetable), you are kindly asked to contact the  teacher via e-mail

Teaching activities

Completion accademic year: 2024/2025

Course year: 4 Full cicle (5 years) PHARMACY A.Y. 2021/2022

Completion accademic year: 2023/2024

Course year: 4 Full cicle (5 years) PHARMACY A.Y. 2020/2021

Completion accademic year: 2022/2023

Course year: 4 Full cicle (5 years) PHARMACY A.Y. 2019/2020

Completion accademic year: 2021/2022

Course year: 4 Full cicle (5 years) PHARMACY A.Y. 2018/2019

Completion accademic year: 2020/2021


Prof Stefania Butini is associate professor of medicinal chemistry since 2015. She earned the degree of chemistry and pharmaceutical technology at the University of Siena in 1997 and a PhD in pharmaceutical sciences at the same University in 2000. In 1999-2000 she spent a period of internship at the University of Groningen under the supervision of Prof H.W. Wikström working on Parkinson Disease and the development of dopamine D3 receptor modulators. In 2004 she became permanent senior researcher at the University of Siena.

Her research activity focuses on the development of bioactive compounds with a special emphasis on CNS diseases, antimalarial, and antitumor agents. Exploration of chemistry and biology of synthetic organic molecules with therapeutic potential in neurodegenerative and neuropsychiatric diseases is a key part her research interests that include target selection, rational design of innovative drugs, discovery of new synthetic methodologies, and general strategies for synthesis, bioinformatics and the study of structure-function relationships. She is experienced as Research Units’ coordinator in National and International polycentric research projects dealing with drug development in various fields.

Ultime pubblicazioni:

  • Fedeli, R., Spizzirri, U.G., Aquino, G., Basilicata, M.G., Pepe, G., Campiglia, P., et al. (2024). Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products. ACS FOOD SCIENCE & TECHNOLOGY [10.1021/acsfoodscitech.4c00098]. - view more
  • Carullo, G., Borghini, F., Fusi, F., Saponara, S., Fontana, A., Pozzetti, L., et al. (2024). Traceability and authentication in agri-food production: A multivariate approach to the characterization of the Italian food excellence elephant garlic (Allium ampeloprasum L.), a vasoactive nutraceutical. FOOD CHEMISTRY, 444 [10.1016/j.foodchem.2024.138684]. - view more
  • Butini, S., Grether, U., Jung, K., Ligresti, A., Allarà, M., Postmus, A.G.J., et al. (2024). Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. JOURNAL OF MEDICINAL CHEMISTRY, 67(3), 1758-1782 [10.1021/acs.jmedchem.3c01278]. - view more
  • Falbo, F., Gemma, S., Koch, A., Mazzotta, S., Carullo, G., Ramunno, A., et al. (2024). Synthetic derivatives of natural cinnamic acids as potential anti-colorectal cancer agents. CHEMICAL BIOLOGY & DRUG DESIGN, 103(1) [10.1111/cbdd.14415]. - view more
  • Rossi, S., Tatangelo, V., Dichiara, M., Butini, S., Gemma, S., Brogi, S., et al. (2024). A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients. BIOMÉDECINE & PHARMACOTHÉRAPIE, 174 [10.1016/j.biopha.2024.116537]. - view more