GIULIANI GERMANO

PERSONAL INFORMATION

Germano Giuliani

 14, via Leoncavallo, Casalecchio di Reno, 40033, Italy

 0577234359     +34646451714       

giuliani5@unisi.it

https://docenti.unisi.it/it/giuliani  

Sex Male | Date of birth 02/08/1970 | Nationality Italian

Enterprise

University

EPR

☐ Management Level

☐ Full professor

☐ Research Director and 1st level Technologist / First Researcher and 2nd level Technologist

☐ Mid-Management Level

☐ Associate Professor

☐ Level III Researcher and Technologist

☐ Employee / worker level

☒ Researcher and Technologist of IV, V, VI and VII     level / Technical collaborator

☐ Researcher and Technologist of IV, V, VI and VII level / Technical collaborator

WORK EXPERIENCE

March 2008 to present

January 2017 to present

January 2005 to 2008)

November 2006 to July 2007)

Assistant Professor

Dipartimento Biotecnologie, Chimica e Farmacia, Università di Siena

• Drug discovery, drug delivery systems, Structure-Activity Relationship (SAR), organic synthesis, heterocyclic chemistry.

Visiting researcher

Institut de Química Computacional i Catàlisis (IQCC) University of Girona (Spain)

• Theoretical modeling and simulation of excited states and non-adiabatic processes, including photochemistry in biochemistry and molecular materials.

Research Associate

Dipartimento Biotecnologie, Chimica e Farmacia, Università di Siena

• Supramolecular chemistry (polymers, dendrimers), structural manipulations of bioluminescent substrate (Coelenterazine)

Visiting researcher

ISS (Istituto Superiore di Sanità) Rome

• Pharmacology characterization of neurokinin (NK1) derivatives, chemi-bioluminescence, and BRET applications.

EDUCATION AND TRAINING

April 2005

PhD in Medicinal Chemistry

Dipartimento Biotecnologie, Chimica e Farmacia, Università di Siena

• “Contributo allo studio del recettore NK1. Sintesi e valutazione biologica di 3-chinolincarbossiammidi e composti correlati.”

                                         July 2000

Master Degree in Chemistry (Analytical Chemistry)

Department of Chemistry, University of Bologna

• “Metodiche voltammetriche per la simultanea determinazione di metalli inquinanti in acque superficiali.”

PERSONAL SKILLS

Mother tongue(s)

Italian

Other language(s)

English (good level)

Spanish (good level)

French (intermediate level)

Job-related skills

Good knowledge of software for computational calculations: Gromacs, Amber, Tinker, Molcas, Gaussian. Supervision and coordination of the synthetic and computational work of the group’s students and PhDs.

Digital skills

Excellent knowledge of MS Office, Unix.

Other skills

Flexibility and problem-solving approach to teamwork.

ADDITIONAL INFORMATION

Publications

1. M Paolino, A Reale, G Magrini, V Razzano, M Saletti, G Giuliani, A Donati, F Samperi, A Scamporrino, M Canetti, M Mauro, F Villafiorita-Monteleone, E Fois, C Botta, A Cappelli, Synthesis and UV-light induced oligomerization of a benzofulvene-based neutral platinum (II) complex. Eur. Polym. J. 2021, 156, 110597.
2. G Giuliani, A Merolla, M Paolino, A Reale, M Saletti, L Blancafort, A Cappelli, F Benfenati, F Cesca. Stability Studies of New Caged bis‐deoxy‐coelenterazine Derivatives and Their Potential Use as Cellular pH Probes. Photochem. Photobiol. 2021, 97, 343-352.
3. G Giuliani, F Melaccio, S Gozem, A Cappelli, M Olivucci. QM/MM Investigation of the Spectroscopic Properties of the Fluorophore of Bacterial Luciferase. J. Chem. Theory Comput. 2021, 17, 605-613.
4. A Reale, S Brogi, A Chelini, M Paolino, A Di Capua, G Giuliani, A Cappelli, G Giorgi, G Chemi, A Grillo, M Valoti, L Sautebin, A Rossi, S Pace, C La Motta, L Di Cesare Mannelli, E Lucarini, C Ghelardini, M Anzini.  Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1, 5-diarylpyrrol-3-substituted scaffold. Bioorg Med Chem 2019, 19, 115045.
5. M Paolino, G Grisci, F Castriconi, A Reale, G Giuliani, A Donati, C Bonechi, G Giorgi, R Mendichi, D Piovani, A Caterina Boccia, M Canetti, F Samperi, S Dattilo, C Scialabba, M Licciardi, E Paccagnini, M Gentile, A Cappelli.Densely PEGylated polybenzofulvene brushes for potential applications in drug encapsulation  Pharmaceutics, 2018, 10, 234.
6. G Valacchi, G Grisci, C Sticozzi, Y Lim, M Paolino, G Giuliani, R Mendichi, G Belmonte, R Artusi, A Zanardi, P Garofalo, G Giorgi, A Cappelli, L Rovati. Wound healing properties of hyaluronan derivatives bearing ferulate residues. J Mater Chem B, 2015, 35, 7037-7045.
7. G Giuliani, P Molinari, G Ferretti, A Cappelli, M Anzini, S Vomero, T Costa. New red-shifted coelenterazine analogues with an extended electronic conjugation. Tetrahedron Letters, 2012, 53, 5114-5118.