PI of a medicinal chemistry research groupthat uses advanced computational studies and biophysical methods to investigate and characterize macromolecular targets, as well as small molecules endowed with pharmacological relevance through the interaction with various types of macromolecules.
MORI MATTIA
Presentation
Office hours
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Friday from 15:00 to 17:00Place: Da definireNote: E' consigliabile mandare una mail al docente per fissare appuntamento
Contacts
0577232360 [int.2360],0577232488 [int.2488] (Stanza 10 173),0577232952 [int.2952] (Stanza 10 106 San Miniato)
Curriculum Vitae
Notices
Availability of EXPERIMENTAL thesis works in computational medicinal chemistry, for students of CTF, Pharmacy, Chemical Sciences and Chemistry degree courses.
Availability of COMPILATION thesis works on topics related to medicinal chemistry and drug discovery, for students of CTF, Pharmacy, Chemical Sciences and chemistry degree courses.
For information on the topic and the timeline, please do not hesitate to contact me via email
Teaching activities
Completion accademic year: 2026/2027
Completion accademic year: 2025/2026
Completion accademic year: 2024/2025
Completion accademic year: 2023/2024
Completion accademic year: 2022/2023
Research
Ultime pubblicazioni:
- Bernardoni, B.L., D'Agostino, I., Siragusa, S., Mori, M., Garavaglia, S., La Motta, C. (2026). A scaffold repositioning approach: dihydroBenzoImidazoTriazineDione (BITD) derivatives as selective ALDH1A1 inhibitors. MOLECULAR DIVERSITY, 30(1), 495-508 [10.1007/s11030-025-11179-6]. - view more
- Platella, C., Trajkovski, M., Brancaccio, M., Di Palma, R., Calcaterra, A., Mori, M., et al. (2026). Selective Delivery of Anticancer Natural G-Quadruplex Ligands by the AT11 Aptamer for Gastric Cancer Treatment. JOURNAL OF MEDICINAL CHEMISTRY, 69(1), 352-367 [10.1021/acs.jmedchem.5c02521]. - view more
- Nocentini, A., Giovannuzzi, S., Alterio, V., Bonardi, A., Barons, R., Zalubovskis, R., et al. (2026). Discovery of a Mixed and Prodrug-Like Inhibition Mechanism for Phosphocoumarins and Phosphoquinolinones against Human Carbonic Anhydrases. JOURNAL OF MEDICINAL CHEMISTRY, 69(9), 11638-11648 [10.1021/acs.jmedchem.6c00915]. - view more
- Cammarone, S., Pastore, V., Ryzhuk, M., Cristoferi, M., Speroni, A., Imperi, F., et al. (2026). Exploration of the aromatic abietane diterpenoid scaffold in the development of ArnT-mediated colistin resistance inhibitors. RSC ADVANCES, 16(12), 11061-11075 [10.1039/d5ra09142j]. - view more
- Bufalieri, F., Cucinotta, A., Cammarone, S., Agnoli, F., Basili, I., Ferri, G., et al. (2026). Discovery of a new selective ERAP1 inhibitor for Hedgehog-dependent cancer treatment. MOLECULAR THERAPY, 34(1), 582-605 [10.1016/j.ymthe.2025.10.036]. - view more