FRULLANTI ELISA

Elisa
Frullanti
Professore Associato

Presentation

Elisa Frullanti completed a PhD in Cancer Genetics of Open University of London at the affiliated center Isitituto Nazionale Tumori (INT, Milan, Italy). She has been working in the field of lung cancer (LC) genetics for 10 years first in Milan, at INT (2006-2012), and then at University of Siena (2013-today) in the Medical Genetics Unit. In INT she conducted her research project aimed to identify functional genetic elements associated with LC prognosis through genome wide association studies, genetic linkage and transcriptome studies winning in 2010 an AIRC Triennal Fellowship. In 2011 she won the Galilei Young Research Scientist Award Rotary International. She is currently Associate Professor of Genetics in the Dept. Medical Biotechnologies at University of Siena. Her main research interests were the dissection of molecular and genetic bases of LC in never smoker young patients and in other diseases following innovative “omics” approaches that integrate genomic and transcriptomic data. 

From 2019, she will be the group leader of a research project funded by MIUR-PRIN 2017 about Gene Therapy in PCDH19 disease. In the last 3 years, EF has introduced in her lab the use of NGS for liquid biopsy as an innovative diagnostic and prognostic technique for the early detection and the dynamical monitoring of cancer growth and resistance, coordinating of 2 PhD students and a Postdoc. In the last 2 years, in response to the COVID-19 pandemic, she devoted part of her research activities to study the genetic basis of the clinical variability of the response to SARS-CoV-2 infection. She has extensive experience in the field of omic genetic techniques, in the next-generation sequencing of both germline, somatic and circulating DNA investigating the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes. She is currently director of the Cancer Genomic and Systems Biology Lab (https://liquidbiopsy.unisi.it/cgsb-lab/) of the Department of Medical Biotechnology of the University of Siena. EF’s research activity is substantiated by 70 original articles in international peer-reviewed scientific journals with a total IF>400 and H-index of 22.

Office hours

  • Wednesday from 16:00 to 17:00
    Place: Dept. of Medical Biotechnologies, University of Siena c/o Polo Scientifico di San Miniato (stanza 10179) Via Aldo Moro, 2 - 53100 - Siena - Italy

Reception hours:

Wednesday from 4 pm to 5 pm (contact by email for an appointment).

Place: Dept. Medical Biotechnologies, c/o Polo Scientifico di San Miniato, 1st Floor Sector B, room n. 10179, Via Aldo Moro, 2 - 53100 - Siena - Italy
Phone: +39 0577 232595

 

 

 

 

Contacts

0577232595 [int.2595]

Curriculum Vitae

Teaching activities

Completion accademic year: 2025/2026

Course year: 2 Second cycle degree (Laurea Magistrale) MEDICAL BIOTECHNOLOGIES A.Y. 2024/2025
Course year: 2 Second cycle degree (Laurea Magistrale) MEDICAL BIOTECHNOLOGIES A.Y. 2024/2025
Course year: 1 Second cycle degree (Laurea Magistrale) BIOTECHNOLOGIES OF HUMAN REPRODUCTION A.Y. 2025/2026
Course year: 1 Second cycle degree (Laurea Magistrale) MEDICAL BIOTECHNOLOGIES A.Y. 2025/2026
Course year: 1 Second cycle degree (Laurea Magistrale) GENETIC COUNSELLORS A.Y. 2025/2026
Course year: 1 First cycle degree (DM 270) BIOMEDICAL LABORATORY TECHNIQUES A.Y. 2025/2026
Course year: 1 First cycle degree (DM 270) BIOMEDICAL LABORATORY TECHNIQUES A.Y. 2025/2026
Course year: 2 Full cicle (6 years) MEDICINA E CHIRURGIA A.Y. 2024/2025
Course year: 4 Full cicle (6 years) MEDICINE AND SURGERY A.Y. 2022/2023

Completion accademic year: 2024/2025

Course year: 1 Second cycle degree (Laurea Magistrale) GENETIC COUNSELLORS A.Y. 2024/2025

Research

Ultime pubblicazioni:

  • Powrózek, T., Otieno, M.O., Maffeo, D., Frullanti, E., Martinez-Useros, J. (2025). Blood circulating miRNAs as pancreatic cancer biomarkers: An evidence from pooled analysis and bioinformatics study. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 308 [10.1016/j.ijbiomac.2025.142469]. - view more
  • Meng, Y., Serio, V.B., Tong, Y., Huang, T., Frullanti, E., Palmieri, M. (2025). Editorial: Recent advancements in RNA-based and targeted therapeutics. FRONTIERS IN GENETICS, 16 [10.3389/fgene.2025.1603498]. - view more
  • Meng, Y., Palmieri, M., Frullanti, E. (2024). Editorial: Lung adenocarcinoma: from genomics to immunotherapy. FRONTIERS IN GENETICS, 15 [10.3389/fgene.2024.1399127]. - view more
  • Maffeo, D., Rina, A., Serio, V.B., Markou, A., Powrózek, T., Constâncio, V., et al. (2024). The Evidence Base for Circulating Tumor DNA-Methylation in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis. CANCERS, 16(21) [10.3390/cancers16213641]. - view more
  • Rosati, D., Palmieri, M., Brunelli, G., Morrione, A., Iannelli, F., Frullanti, E., et al. (2024). Differential gene expression analysis pipelines and bioinformatic tools for the identification of specific biomarkers: A review. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 23, 1154-1168 [10.1016/j.csbj.2024.02.018]. - view more